Cryo-Electron Microscopy in Structural Biology: From Structural Insights to Tomography and Drug Discovery
Krishnarao Appasani's newest release offers an intricate examination of Cryo-Electron Microscopy (cryo-EM) and its transformative influence on the realm of structural biology. This detailed tome plunges into the avant-garde technology that facilitates the observation of molecular architectures at extraordinary resolutions, often eclipsing the remarkable threshold of 1 Å. The text delivers authoritative insights into cryo-EM methodologies from dual standpoints: structural and biological, rendering it an indispensable asset for investigators, postgraduate scholars, and specialists within biophysics, structural biology, crystallography, and genomics. Appasani diligently scrutinizes the myriad applications of cryo-EM across diverse domains, such as membrane and viral research, the biochemistry of cellular organelles, and the intricate mechanisms of nuclear and genetic activity. A noteworthy segment of this volume is devoted to the exciting potential of cryo-EM in the realms of pharmacological discovery and therapeutic innovation. Emphasizing high-resolution structural revelations and the seamless integration of tomography, this remarkable work serves as an essential compass for those eager to grasp the cutting-edge landscape of molecular visualization techniques in biological inquiry.
- Author: Krishnarao Appasani
- Publisher: CRC Press; 1st edition (17 October 2024)
- Genre: Medicine & Healthcare
- ISBN: 978-1032352534
- Pages: 464 pages